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ALA Research

In type-II diabetes, insulin resistance, rather than a lack of insulin, is the cause of
elevated blood glucose levels. A small number of clinical studies have reported the
benefits of high doses of racemic Lipoic Acids in improving insulin sensitivity.
Animal studies have suggested higher benefit levels from R-isomer of Lipoic Acid as
compared to its S-isomer. However, clinical studies are required to prove this
benefit. Evidence of Lipoic Acid-induced reduction of oxidative stress in diabetic
patients needs to be established with further studies.

The beneficial effects of ALA treatment on symptoms of diabetic neuropathy have
been observed in at least 15 clinical trials. Many short-term preliminary studies in
humans have stated that Lipoic Acid administration can reduce the risk of vascular
complications in diabetic (type I and type II) patients.

Several studies in aging rats have reported that short-term combined dietary
supplementation with R-alpha Lipoic Acid and acetyl-L-carnitine improved
mitochondrial energy metabolism, decreased oxidative stress, and had positive
effects on physical activity and short-term memory. However, long-term studies on
humans are needed to prove similar effects. In a short-term research study, Lipoic
Acid has been found to significantly increase plasma vitamin C and glutathione in
HIV-infected patients. In a Russian study, Lipoic Acids ability to reduce free radical
damage caused by radiation exposure has been observed.

Animal studies have reported the use of Lipoic Acid in the prevention of cell damage
in stroke and congestive cardiac failure patients. Extensive animal studies have
shown the significant protective effects of Lipoic Acid against ischemia-reperfusion
injury. Animal studies on Lipoic Acid have also proposed its benefit in the treatment
of several neurodegenerative disorders, including Alzheimer's disease, Parkinson's
disease, and Huntington's disease. While the results of animal studies are
encouraging, long-term, placebo-controlled, randomized clinical trials are needed for
its confident prescription.

Alpha Lipoic Acid provides detailed information on alpha lipoic acid, ALA products,
ALA research, ALA side effects and more. Alpha Lipoic Acid is affliated with Uses
and Benefits.

Article Source: http://EzineArticles.com/?expert=Jimmy_Sturo
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